Season all sides of the brisket with the seasoning mix.
Place the brisket on the smoker and allow to smoke for 8-10 hours, or until the internal temperature is 165 degrees.
Wrap the brisket in butcher paper and place back on the grill. Allow it to smoke for another 4-6 hours or until the internal temperatuer is 202 and the brisket is probe tender.
Remove the brisket from the grill and allow it to sit at room temperature on your cutting board for an hour.